Over 2,000 black and white men and women ages 70-79 years old were asked to complete a questionnaire to determine how much magnesium they were receiving from food and various supplements. Additionally, researchers performed bone mineral density tests on the participants.

The study revealed that those who ingested more magnesium had significantly higher bone density than those who got the least amount of magnesium. For every 100 milligram per day increase in magnesium intake, data showed a 1% increase in bone density.

However, this link was only true for the older white men and women. Previous research has demonstrated that black men and women may process vitamin D and other calcium regulating hormones differently than whites, thus possibly explaining the lack of association between magnesium and bone density among them in this study.

Although this [1% increase] seems small, increases across a population may have large public health impact, states lead researcher Kathryn M. Ryder.

The recommended daily allowance of magnesium is 320 mg/day for women and 420/mg day for men in this age group. Most people in this age group get far less than this daily amount.

blackwellpublishing/jgs

Potential causes of esophageal adenocarcinoma were identified by Mayne and her colleagues in a previously completed population-based, multi-center study of 1,095 cancer patients and 687 control subjects. As part of that study, they conducted a full dietary interview and had access to available data on consumption of both regular and diet soft drinks.

"Our team analyzed that data as the first direct test of the hypothesis that soft drinks might have contributed to the increase in this cancer," said Mayne. "We found that contrary to the hypothesis put forth by other researchers, carbonated soft drink consumption was inversely associated with esophageal adenocarcinoma risk, mainly attributable to diet soda, and that high intake did not increase risk of any esophageal or gastric cancer subtype in men or women."

Other Yale authors on the study included Harvey Risch, principal investigator of the grant that supported the work, Robert Dubrow, and Mayne's former student, Lauren Borchardt. Authors from other centers included Wong-Ho Chow, Marilie D. Gammon, Thomas L. Vaughan, Janet B. Schoenberg, Janet L. Stanford, A. Brian West, Heidi Rotterdam, William J. Blot and Joseph F. Fraumeni, Jr.

yale/